VU6043653

SKU: orb2802263

Description

VU6043653 is a potent, selective, and brain-penetrant negative allosteric modulator of the mGlu5 receptor, exhibiting an IC50 of 325 nM at the human receptor. It is a valuable research tool for investigating mGlu5 function in neurological and psychiatric disorders, suitable for both in vitro binding assays and in vivo behavioral studies.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 3032791-06-0
• MW: 327.31
• Formula: C₁₆H₁₄FN₅O₂
• SMILES: O=C(NC1=NC=C(F)C=C1)C=2N=C(C=C(OC=3C=NN(C3)C)C2)C
• Target: ROCK,HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171092011