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VU590

SKU: orb1703932

Description

VU590 is a potent, moderately selective inhibitor of the extrarenal medullary potassium channel ROMK (Kir1.1). It also inhibits Kir7.1 and has been used in research to study uterine contractility and melanocortin signaling pathways in both in vitro and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number313505-85-0
MW488.53
Purity99.11% (May vary between batches)
FormulaC24H32N4O7
SMILESCl.Cl.[O-][N+](=O)c1ccc(CN2CCOCCOCCN(Cc3ccc(cc3)[N+]([O-])=O)CCOCC2)cc1
TargetPotassium Channel
SolubilityH2O:1 mg/mL (2.05 mM);DMSO:< 20 mg/mL

Bioactivity

Target IC50
Kir1.1:290 nM|Kir7.1:8 μM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

PotassiumChannel, Potassium Channel, ROMK, VU590, VU-590, VU590 (hydrochloride), VU-590 (hydrochloride), VU 590, Kir1.1

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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2 mg
$ 80.00
5 mg
$ 100.00
10 mg
$ 140.00
25 mg
$ 210.00
50 mg
$ 290.00
100 mg
$ 420.00
DispatchUsually dispatched within 5-10 working days
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