VU0514009

SKU: orb3135164

Description

VU0514009 is a competitive antagonist of chemokine-like receptor 1 (CMKLR1) with an EC50 of 2 nM. It effectively inhibits chemerin-9-induced arrestin recruitment and receptor internalization, significantly reducing Ca2+ flux responses in HEK293 cells. This compound shows potential for research in inflammatory diseases and metabolic syndrome.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 932973-77-8
• MW: 493.984
• Formula: C₂₁H₂₀ClN₃O₅S₂
• SMILES: COC1=CC=C(C)C=C1NC(=O)CSC1=NC=C(C(=O)N1)S(=O)(=O)C1=CC(Cl)=C(C)C=C1
• Target: Chemerin Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Chemerin Receptor