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VU0453379

SKU: orb2279256

Description

VU0453379 is a brain-penetrant, selective positive allosteric modulator of the GLP-1 receptor with an EC50 of 1.3 µM. It is a valuable research tool for investigating central GLP-1R signaling in models of metabolic and neurodegenerative diseases, applicable in both in vitro and in vivo studies.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1638646-27-1
MW434.57
FormulaC26H34N4O2
SMILESC(NC[C@H]1N(C(C)C)CCC1)(=O)C=2C3=C(N(C)C=4C3=CC=CC4)C(=O)N(C2)C5CCCC5
TargetOthers,Glucagon Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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VU0453379 (orb2279256)

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