VU0155069

SKU: orb1706475

Description

VU0155069 is a potent and selective phospholipase D1 (PLD1) inhibitor with an in vitro IC50 of 46 nM. It has been shown to strongly suppress the invasive migration of various cancer cell lines in transwell assays, making it a valuable research tool for studying cancer metastasis and PLD1 signaling pathways in cellular models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1130067-06-9
• MW: 462.97
• Purity: 99.50% (May vary between batches)
• Formula: C₂₆H₂₇ClN₄O₂
• SMILES: Cl.C[C@@H](CN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O)NC(=O)c1ccc2ccccc2c1
• Target: Phospholipase
• Solubility: DMSO:45 mg/mL (97.2 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.32 mM)

Bioactivity

• Target IC50:
  PLD1:46 nM|PLD2:933 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PLD1, PLD2, CAY 10593, CAY10593, CAY-10593, VU 0155069, VU0155069, VU-0155069

Compound Identifiers

PubChem CID

56972237