VU 0364739 hydrochloride

SKU: orb1703933

Description

VU 0364739 hydrochloride

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 1244640-48-9
• MW: 482.98
• Purity: 99.36%
• Formula: C₂₆H₂₈ClFN₄O₂
• SMILES: Cl.O=C(NCCN1CCC2(C(=O)NCN2C=3C=CC=C(F)C3)CC1)C=4C=CC=5C=CC=CC5C4
• Target: Phospholipase,Apoptosis
• Solubility: DMSO:10 mg/mL (20.7 mM)

Bioactivity

• Target IC50:
  PLD2:20 nM|PLD1:1500 nM
• In Vitro:
  MDA-MB-231 cells were cultured in the presence of VU 0364739 hydrochloride (1, 5, and 10 μM) for 24, 48, 72, and 96 hours, followed by determination of cell viability using the WST-1 cell proliferation reagent. The results indicate that VU 0364739 hydrochloride significantly reduces proliferation of MDA-MB-231 cells in a dose- and time-dependent manner.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

VU0364739 Hydrochloride, VU-0364739 Hydrochloride, VU 0364739 HCl, Apoptosis, PLD2

Compound Identifiers

PubChem CID

46939225