VU 0285683

SKU: orb1703936

Description

VU 0285683 is a potent and selective negative allosteric modulator targeting the mGluR5 receptor at the MPEP site. It exhibits anxiolytic-like effects in vivo and is a valuable research tool for investigating neurological disorders such as anxiety, depression, and Fragile X syndrome in both cellular and animal models.

Research Area

Neuroscience

Key Properties

• CAS Number: 327056-22-4
• MW: 266.23
• Purity: 99.98% (May vary between batches)
• Formula: C₁₄H₇FN₄O
• SMILES: C(#N)C=1C=C(C=C(F)C1)C2=NC(=NO2)C3=CC=CC=N3
• Target: GluR
• Solubility: DMSO:9 mg/mL (33.81 mM);Ethanol:6 mg/mL (22.54 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

VU0285683, VU-0285683, VU 0285683, mGluR5

Compound Identifiers

PubChem CID

9816778