VTP50469 mesylate

SKU: orb1739634

Description

VTP-50469 is a potent, selective, and orally bioavailable Menin-MLL1 interaction inhibitor. It demonstrates efficacy in preclinical models of MLL-rearranged and NPM1-mutant leukemias, showing selective cytotoxicity in relevant cell lines and anti-leukemic activity in vivo.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• CAS Number: 2169919-27-9
• MW: 726.9244
• Formula: C₃₃H₅₁FN₆O₇S₂
• SMILES: CS(O)(=O)=O.CS(O)(=O)=O.CC(C)N(C(C)C)C(=O)c1cc(F)ccc1Oc1cncnc1N1CC2(C1)CCN(C[C@H]1CC[C@@H](CC1)NS(C)(=O)=O)CC2
• Target: Others,Apoptosis,Epigenetic Reader Domain

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

132212961