VTP50469 fumarate

SKU: orb1708228

Description

VTP50469 fumarate is a potent, orally bioavailable small molecule that selectively inhibits the Menin-MLL interaction with picomolar affinity. It demonstrates robust anti-leukemic efficacy in both cellular assays and in vivo models, making it a valuable chemical probe for researching MLL-rearranged leukemias.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• CAS Number: 2169919-29-1
• MW: 1609.86
• Formula: C₇₆H₁₀₆F₂N₁₂O₂₀S₂
• SMILES: OC(/C=C/C(O)=O)=O.CC(C)N(C(C)C)C(C(C=C(C=C1)F)=C1OC2=CN=CN=C2N(C3)CC3(CC4)CCN4C[C@@H]5CC[C@H](CC5)NS(C)(=O)=O)=O.CC(C)N(C(C)C)C(C(C=C(C=C6)F)=C6OC7=CN=CN=C7N(C8)CC8(CC9)CCN9C[C@@H]%10CC[C@H](CC%10)NS(C)(=O)=O)=O.OC(/C=C/C(O)=O)=O.OC(/C=C/C(O)=O)=O
• Target: Epigenetic Reader Domain,Others,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168012211