VSLRGDTRG

SKU: orb3023020

Description

VSLRGDTRG is a synthetic peptide derived from the RGD motif in cadherin17 (CDH17) that binds to the α2β1 integrin, activating its signaling pathways. By promoting high-affinity conformational changes in β1 integrins through the RGD motif, VSLRGDTRG enhances cell adhesion and the phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. This peptide is useful for research on cancers expressing CDH17, such as colorectal and pancreatic cancer.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• Target: ERK,Integrin,FAK
• CAS Number: 2027476-29-3
• MW: 960.047
• Formula: C₃₈H₆₉N₁₅O₁₄
• SMILES: [C@@H](NC([C@@H](NC([C@@H](NC([C@H](C(C)C)N)=O)CO)=O)CC(C)C)=O)(C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(NCC(O)=O)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)=O)CCCNC(=N)N

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

ERK,Integrin,FAK