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VR11 aptamer

SKU: orb3177400

Description

VR11 aptamer is a DNA-based TNF-α inhibitor with a KD of 7.0 nM. It effectively blocks TNFα-induced apoptosis (apoptosis) and prevents NO production. VR11 aptamer demonstrates no immunogenicity as it does not trigger an immune response when administered intraperitoneally in C57BL/6 mouse models. This aptamer is suitable for research on inflammatory diseases.

Research Area

Cell Biology, Immunology & Inflammation

Images & Validation

Key Properties

TargetTNF,Apoptosis,NO Synthase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information