VPC285785

SKU: orb3211043

Description

VPC285785 is an orally active inhibitor of the SARS-CoV-2 main protease, with an IC50 of 0.8 μM and a Kd of 2.7 μM. It functionally inhibits the processing of viral polyprotein precursors by the viral main protease, necessary for viral replication. VPC285785 reduces viral load in liver, brain, and spleen tissues in MHV-infected mice. This compound is applicable for research on coronavirus infections.

Key Properties

• CAS Number: 2759276-10-1
• MW: 469.48
• Formula: C₂₄H₂₅F₂N₅O₃
• SMILES: C(N[C@@H](C[C@H]1C(=O)NCC1)C#N)(=O)[C@@H]2[C@@]3([C@@](C3(C)C)(CN2C(=O)C4=CC=5C(N4)=CC(F)=CC5F)[H])[H]
• Target: SARS-CoV

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

SARS-CoV