Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Votoplam HCl

SKU: orb2944172

Description

Votoplam HCl (PTC-518 HCl) is a small molecule splicing modulator that reduces huntingtin protein levels. It is utilized in preclinical research for Huntington's disease, with studies demonstrating its activity in both cellular and animal models of HD.

Research Area

Cell Biology, Molecular Biology, Neuroscience

Images & Validation

Key Properties

CAS Number2407851-28-7
MW455.94
Purity99.02%
FormulaC21H26ClN9O
SMILESCl.OC=1C=C(C=CC1C2=NN=C3C(N=NN3C4CC(NC(C)(C)C4)(C)C)=C2)N5N=CC=N5
TargetHuntingtin,DNA/RNA Synthesis

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

PTC518 HCl, PTC-518 HCl, Votoplam HCl(2407849-89-0 Free base)
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

Votoplam HCl (orb2944172)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 340.00
5 mg
$ 770.00
10 mg
$ 1,030.00
DispatchUsually dispatched within 5-10 working days
Bulk Enquiry