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Vorolanib

SKU: orb1298889

Description

Vorolanib (X-82) is an orally active dual inhibitor of VEGFR and PDGFR used in research on angiogenesis, particularly in oncology and ophthalmology. Studies report its activity in in vitro cell-based assays and in vivo tumor and ocular neovascularization models, based on publicly available literature.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

Key Properties

CAS Number1013920-15-4
MW439.48
Purity98.73% (May vary between batches)
FormulaC23H26FN5O3
SMILESCN(C)C(=O)N1CC[C@@H](C1)NC(=O)c1c(C)[nH]c(\C=C2\C(=O)Nc3ccc(F)cc23)c1C
TargetPDGFR,VEGFR
SolubilityDMSO:22 mg/mL (50.06 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.55 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ABC, ABCG2, angiogenesis, ATP-binding, CM082, CM 082, CM-082, cassette, inhibit, kinase, orally, Platelet-derived growth factor receptor, Inhibitor, HUVECs, X 82, X82, X-82, TKI, PDGFR, Vascular endothelial growth factor receptor, VEGFR, Vorolanib, transporter, tyrosine

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 150.00
2 mg
$ 200.00
5 mg
$ 280.00
1 ml x 10 mM (in DMSO)
$ 310.00
10 mg
$ 420.00
25 mg
$ 690.00
50 mg
$ 980.00
100 mg
$ 1,310.00
200 mg
$ 1,730.00
DispatchUsually dispatched within 5-10 working days
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