VNPP433-3β

SKU: orb2564552

Description

VNPP433-3β is a molecular glue degrader targeting the androgen receptor (AR), its splice variants, and Mnk1/2. It potently inhibits prostate cancer cell proliferation in vitro and demonstrates in vivo efficacy by suppressing tumor growth in a CWR22Rv1 xenograft model.

Research Area

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 1630820-51-7
• MW: 438.61
• Formula: C₂₉H₃₄N₄
• SMILES: C[C@@]12[C@]([C@]3([C@](CC1)([C@]4(C)C(=CC3)C[C@H](CC4)N5C=CN=C5)[H])[H])(CC=C2N6C=7C(N=C6)=CC=CC7)[H]
• Target: Molecular Glues,Androgen Receptor,MNK,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

85468997