VMAPRTLFL

SKU: orb3180329

Description

VMAPRTLFL is a 9-peptide derived from the HLA-G signal peptide and serves as a ligand for the HLA-E peptide. It plays a crucial role in regulating the function of adaptive natural killer (NK) cells. VMAPRTLFL specifically enriches FcεRγ-adaptive NK cells, upregulates CD25 expression, and enhances their proliferation, antibody-dependent cellular cytotoxicity (ADCC), and IFN-γ release. This peptide can be utilized in research related to human cytomegalovirus (HCMV) infection, transplant rejection, and pregnancy immunity.

Key Properties

• Target: MHC
• CAS Number: 202657-61-2
• MW: 1047.33
• Formula: C₄₉H₈₂N₁₂O₁₁S
• SMILES: C([C@@H](NC([C@@H](NC([C@H](C(C)C)N)=O)CCSC)=O)C)(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)CC(C)C)=O)[C@@H](C)O)=O)CCCNC(=N)N)=O)CCC1

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

MHC