Vitamin D2

SKU: orb1224925

Description

Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.(In Vivo):At sacrifice, after 5 weeks of treatment, chickens receiving omeprazole alone or omeprazole in combination with either restricted food intake or Ergocalciferol weighed 15-25% less (P < 0.01) than chickens given vehicle or receiving reduced amount of food.Combined treatments of fasting and ergocalciferol show more deleterious effects on growth than fasting only or ergocalciferol only and induced face anomalies.

Key Properties

• CAS Number: 50-14-6
• MW: 396.65
• Purity: >98% (HPLC)
• Formula: C₂₈H₄₄O
• SMILES: O[C@@H]1C/C(C(CC1)=C)=C/C=C2[C@]3([H])CC[C@H]([C@H](C)/C=C/[C@H](C)C(C)C)[C@@]3(C)CCC/2
• Target: DNA/RNA Synthesis
• Solubility: Ethanol: 80 mg/mL (201.68 mM); DMSO: 20 mg/mL (50.42 mM)

Bioactivity

• In Vivo:
  At sacrifice, after 5 weeks of treatment, chickens receiving omeprazole alone or omeprazole in combination with either restricted food intake or Ergocalciferol weighed 15-25% less (P < 0.01) than chickens given vehicle or receiving reduced amount of food. Combined treatments of fasting and ergocalciferol show more deleterious effects on growth than fasting only or ergocalciferol only and induced face anomalies. Animal model: 83 chickens (White Leghorn), weighing 318 ± 9 g. Dosage: 250, 000 IU/kg. Administration: S. C. once daily. Result: Induced a long-lasting hypercalcemia in rat and mice and suppresses the expression of PTH mRNA in the rat.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Calciferol | Ergocalciferol | Fortodyl | Infron | Mulsiferol | NSC 62792 | Radiostol | Uvesterol D

Quick Database Links

Gene Symbol

DNA/RNA Synthesis