ε-​Viniferin

SKU: orb1309694

Description

Epsilon-Viniferin, a resveratrol dimer, is a broad-spectrum cytochrome P450 inhibitor, suppressing activities of human CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2E1, CYP3A4, and CYP4A. This compound is a valuable research tool for studying drug metabolism, enzyme kinetics, and chemical carcinogenesis in both in vitro and cellular assay systems.

Research Area

Metabolism Research

Key Properties

• CAS Number: 62218-08-0
• MW: 454.47
• Purity: 99.98% (May vary between batches)
• Formula: C₂₈H₂₂O₆
• SMILES: Oc1ccc(\C=C\c2cc(O)cc3O[C@H]([C@@H](c23)c2cc(O)cc(O)c2)c2ccc(O)cc2)cc1
• Target: Cytochromes P450
• Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:1.67 mg/mL (3.67 mM);DMSO:75 mg/mL (165.03 mM)

Bioactivity

• Target IC50:
  CYP3A4:10 μM （Ki,TST） |CYP2B6:3 μM （Ki,BROD）|CYP1A2:5 μM （Ki,EROD）|CYP4A:15 μM(LwOH)|CYP2E1:25 μM (CHZ)|CYP2A6:60 μM （Ki,COH）

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CHZ, CYP2B6, CYP2A6, CYP1A2, Cytochrome P450, CYP3A4, CYP2E1, CYPs, CYP4A, inhibit, epsilon-Viniferin, Inhibitor, ε​Viniferin, ε-?Viniferin, ε-Viniferin, ε ​Viniferin

Compound Identifiers

PubChem CID

5281728