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Viloxazine

SKU: orb1689691

Description

Viloxazine is a dual-acting small molecule that inhibits norepinephrine reuptake and modulates serotonin receptors, acting as a 5-HT2C agonist and 5-HT2B antagonist. It is utilized in neuroscience research for studying depression and related disorders in both in vitro and in vivo experimental models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number46817-91-8
MW237.29
Purity99.65% (May vary between batches)
FormulaC13H19NO3
SMILESO(CC1CNCCO1)C2=C(OCC)C=CC=C2
TargetNorepinephrine,5-HT Receptor,Adrenergic Receptor
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (10.54 mM);DMSO:60 mg/mL (252.86 mM)

Bioactivity

Target IC50
5-HT2B:27 μM|5-HT2C:32 μM(EC50)
In Vivo
Viloxazine (1-16 mg/kg; spinal rat) stimulated the hind limb flexor reflex in the dose-dependent manner.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

5HT Receptor, 5-HT2C, 5-HT2B, 5HTReceptor, Emovit, norepinephrine reuptake, Viloxazin, Viloxazine

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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

Viloxazine (orb1689691)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 ml x 10 mM (in DMSO)
$ 70.00
10 mg
$ 70.00
25 mg
$ 100.00
50 mg
$ 140.00
100 mg
$ 190.00
500 mg
$ 410.00
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