VHR-IN-6

SKU: orb3173845

Description

VHR-IN-6 is a selective inhibitor of the vaccinia H1-related (VHR) phosphatase, with an IC50 value of 74 nM. It exhibits comparatively weaker inhibitory activity against MKP-1 (IC50 = 0.52 μM), CD45 (IC50 = 0.50 μM), Cdc25A (IC50 = 2.8 μM), PTP1B (IC50 = 0.42 μM), and HePTP (IC50 = 0.87 μM). Additionally, VHR-IN-6 can suppress the proliferation of HeLa cells and is applicable for cervical cancer research.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1146616-16-1
• MW: 595.68
• Formula: C₂₈H₂₂FN₃O₅S₃
• SMILES: C(\C=1C(=NN(C1)C2=CC=CC=C2)C3=CC=C(OCC4=C(F)C=CC=C4)C=C3)=C\5/C(=O)N(CCS(=O)(=O)O)C(=S)S5
• Target: Phosphatase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Phosphatase