rel-(1R,2R)-Vesamicol Hydrochloride

SKU: orb1704759

Description

rel-(1R,2R)-Vesamicol Hydrochloride is a stereoisomer of Vesamicol HCl, used as a pharmacological tool in neuroscience research. It acts as a vesicular acetylcholine transport (VAChT) inhibitor, facilitating studies of cholinergic systems in both in vitro and in vivo experimental models.

Research Area

Cancer Biology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 120447-62-3
• MW: 295.85
• Purity: 99.88% (May vary between batches)
• Formula: C₁₇H₂₆ClNO
• SMILES: Cl.OC1CCCCC1N1CCC(CC1)C1=CC=CC=C1
• Target: Sigma receptor,AChR
• Solubility: Ethanol:< 5.92 mg/mL;DMSO:18.7 mg/mL (63.21 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.76 mM)

Bioactivity

• Target IC50:
  σ2 receptor:34 nM (Ki)|Acetylcholine transport (vesicular):2 nM (Ki)|σ1 receptor:26 nM (Ki)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AH 5183 Hydrochloride, AH5183 Hydrochloride, AH-5183 Hydrochloride, AChR, (±)-AH5183 hydrochloride, Vesamicol Hydrochloride

Compound Identifiers

PubChem CID

212231