Verucopeptin

SKU: orb2695133

Description

Verucopeptin is a pyranized cyclic peptide antibiotic that acts as a hypoxia-inducible factor 1 (HIF-1) inhibitor. It demonstrates anticancer activity by reducing HIF-1α protein levels and target gene expression, as shown in studies using B16 melanoma models for cancer research.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• Target: HIF/HIF Prolyl-Hydroxylase,Proton pump,HIF,Endogenous Metabolite
• CAS Number: 138067-14-8
• MW: 896.08
• Formula: C₄₃H₇₃N₇O₁₃
• SMILES: N(C([C@@](C)(O)C1(O)O[C@H](\C(=C\[C@H](C[C@H](C[C@@H](CC)C)C)C)\C)[C@@H](OC)CC1)=O)[C@H]2[C@H](C(C)C)OC(=O)CN(C)C(=O)CNC(=O)CN(C)C(=O)CN(O)C(=O)[C@@]3(N(C2=O)NCCC3)[H]

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

121231434