Verubecestat tosylate

• Catalog Number: orb1739376
• Category: Small Molecules
• Description: Verubecestat tosylate
• CAS Number: 1875153-95-9
• Purity: 0.98
• MW: 510.627
• SMILES: Cc1ccc(cc1)S(O)(=O)=O.CN1C(N)=N[C@@](C)(CS1(=O)=O)c1cc(NC(=O)c2ccc(F)cn2)ccc1F
• Formula: C₂₅H₂₆N₄O₄S₂
• Biological Activity: Verubecestat tosylate, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat tosylate is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat tosylate reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.