Verubecestat TFA

SKU: orb1737595

Description

Verubecestat TFA (MK-8931) is a potent, selective BACE1 inhibitor investigated as a therapeutic candidate for Alzheimer's disease. In clinical studies, it demonstrated a reduction of up to 92% in Aβ levels in cerebrospinal fluid and was reported to be well tolerated. Its application extends to in vitro and in vivo research on amyloid precursor protein processing and beta-amyloid pathology.

Research Area

Immunology & Inflammation, Neuroscience

Key Properties

• CAS Number: 2095432-65-6
• MW: 523.435
• Formula: C₁₉H₁₈F₅N₅O₅S
• SMILES: OC(=O)C(F)(F)F.CN1C(=N)N[C@@](C)(CS1(=O)=O)c1cc(NC(=O)c2ccc(F)cn2)ccc1F
• Target: Others,Beta-Secretase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

129896720