Verubecestat TFA

• Catalog Number: orb1737595
• Category: Small Molecules
• Description: Verubecestat TFA
• CAS Number: 2095432-65-6
• Purity: 0.98
• MW: 523.435
• SMILES: OC(=O)C(F)(F)F.CN1C(=N)N[C@@](C)(CS1(=O)=O)c1cc(NC(=O)c2ccc(F)cn2)ccc1F
• Formula: C₁₉H₁₈F₅N₅O₅S
• Biological Activity: Verubecestat TFA, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat TFA is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat TFA reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.