Venuloside A

SKU: orb2564256

Description

Venuloside A (ESK246) is a natural monoprostane glycoside that acts as a specific LAT3 (SLC43A1) inhibitor, blocking leucine transport. This compound is a valuable research tool for studying amino acid dependency in cancer models, including in vitro and in vivo investigations related to prostate cancer.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1609278-97-8
• MW: 424.53
• Purity: >99.99% (May vary between batches)
• Formula: C₂₃H₃₆O₇
• SMILES: O(C(C)(C)[C@@H]1CCC(C)=CC1)[C@H]2[C@H](OC(C)=O)[C@@H](OC(C=C(C)C)=O)[C@@H](O)[C@@H](C)O2
• Target: transporter
• Solubility: DMSO:245 mg/mL (577.11 mM)

Bioactivity

• Target IC50:
  LNCaP cells:8.12 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Absolutestereochemistryshown,Rotation(+), LAT3, ESK246

Compound Identifiers

PubChem CID

122180069