Venetoclax N-oxide

SKU: orb1983276

Description

Venetoclax N-oxide is a metabolite and impurity of Venetoclax (ABT-199), a potent, selective, and orally bioavailable Bcl-2 inhibitor with sub-nanomolar affinity (Ki < 0.01 nM). This small molecule is widely used in oncology research, particularly for studying apoptosis in hematological cancers, in both cellular and animal models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	2469279-00-1
MW	884.44
Formula	C₄₅H₅₀ClN₇O₈S
SMILES	CC1(C)CCC(CN2(=O)CCN(CC2)c2ccc(C(=O)NS(=O)(=O)c3ccc(NCC4CCOCC4)c(c3)N(=O)=O)c(Oc3cnc4[nH]ccc4c3)c2)=C(C1)c1ccc(Cl)cc1
Target	Others,Drug Metabolite

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

139024764 ↗

Key Properties

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No computed properties available.

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