VEGFR/PARP-IN-1

SKU: orb2277792

Description

VEGFR/PARP-IN-1 (Compound 14b) is a dual VEGFR and PARP inhibitor with IC50 values of 191 nM and 60.9 nM, respectively. It exhibits antiproliferative activity in BRCA wild-type breast cancer cell lines (e.g., MDA-MB-231, MCF-7) by inducing cell cycle arrest and apoptosis, supporting its investigation in oncology research for potential antitumor effects.

Research Area

Cardiovascular Research, Cardiovascular Research; Cell Biology, Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Key Properties

• MW: 517.58
• Formula: C₂₉H₂₇N₉O
• Target: PARP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PARP