VEGFR-IN-4

SKU: orb2565073

Description

VEGFR-IN-4 (Compound 6e) is a potent EGFR inhibitor, exhibiting strong antiproliferative activity with an IC50 of 24.6 nM in the HCC827 non-small cell lung cancer cell line. This small molecule is a valuable tool for in vitro cancer research, particularly in studies of EGFR-driven proliferation and signaling pathways.

Research Area

Cardiovascular Research, Cardiovascular Research; Cell Biology, Signal Transduction

Key Properties

• CAS Number: 3000483-29-1
• MW: 446.91
• Formula: C₁₉H₁₉ClN₆O₃S
• SMILES: N(C1=C(C(NO)=O)SC=C1)C2=NC(NC3=CC=C(C=C3)N4CCOCC4)=NC=C2Cl
• Target: EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168866714