VEGFR-2/BRAF-IN-2

SKU: orb1744793

Description

VEGFR-2/BRAF-IN-2 is a dual kinase inhibitor with potent activity against VEGFR-2, BRAF V600E, and BRAF WT (IC50 values: 0.111 µM, 0.089 µM, and 0.071 µM, respectively). It induces apoptosis and G1 phase cell cycle arrest, making it a useful research tool for studying angiogenesis and oncogenic signaling in cancer models.

Research Area

Cardiovascular Research, Cardiovascular Research; Cell Biology, Cell Biology, Signal Transduction

Key Properties

• MW: 608.05
• Formula: C₂₆H₂₁ClF₃N₅O₃S₂
• SMILES: C1CCC2=C(C1)C3=C(S2)N=C(N(C3=O)C4=CC=C(C=C4)Cl)SCC(=O)NNC(=O)NC5=CC=CC(=C5)C(F)(F)F
• Target: Others,VEGFR,Raf,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163409144