VEGFR-2-IN-61

SKU: orb2945184

Description

VEGFR-2-IN-61 (Compound 7b) is a small molecule VEGFR-2 inhibitor with an IC50 of 2.83 µM. It demonstrates anti-cancer activity in vitro by inhibiting MCF-7 cell proliferation (IC50=2.12 µM), suppressing migration, and inducing oxidative stress and apoptosis, supporting its use in angiogenesis and oncology research.

Research Area

Cardiovascular Research, Cardiovascular Research; Cell Biology, Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• MW: 435.52
• Formula: C₂₇H₂₅N₅O
• SMILES: CC(C)C1=CC=C(C=C1)NC(=O)C2=C(N(N=C2C3=CNC4=CC=CC=C43)C5=CC=CC=C5)N
• Target: Apoptosis,Reactive Oxygen Species,ROS,VEGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677038