VEGFR-2-IN-58

SKU: orb2945650

Description

VEGFR-2-IN-58 (Compound 7b) is a potent and selective VEGFR-2 inhibitor (IC50 = 42.5 nM) with anticancer activity. It induces G2/M cell cycle arrest, promotes apoptosis via BAX/Bcl-2 modulation, and inhibits cell migration in vitro, supporting its use in angiogenesis and oncology research.

Research Area

Cardiovascular Research, Cardiovascular Research; Cell Biology, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 3066972-97-9
• MW: 397.856
• Formula: C₂₄H₁₆ClN₃O
• SMILES: C1=CC=C(C=C1)C2=C(OC(=C2C#N)/N=C/NC3=CC=C(C=C3)Cl)C4=CC=CC=C4
• Target: Apoptosis,VEGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176455470