VEGFR-2-IN-36

SKU: orb2277969

Description

VEGFR-2-IN-36 is a potent and selective VEGFR-2 kinase inhibitor (IC50 = 0.067 μM) with pro-apoptotic activity. It demonstrates anticancer efficacy in vitro by upregulating BAX and downregulating Bcl-2, showing cytotoxicity against MCF-7 and HepG2 cell lines. This compound is a valuable tool for angiogenesis and oncology research.

Research Area

Cardiovascular Research, Cardiovascular Research; Cell Biology, Cell Biology, Signal Transduction

Key Properties

• MW: 489.48
• Formula: C₂₄H₂₃N₇O₅
• Target: Apoptosis,Bcl-2 Family,VEGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,Bcl-2 Family,VEGFR