VEGFR-2-IN-29

SKU: orb1297758

Description

VEGFR-2-IN-29 is a potent and selective small molecule inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2). It is a valuable research tool for studying angiogenesis and has demonstrated utility in both in vitro kinase assays and in vivo models of cancer and other pathologies involving VEGFR2 signaling.

Research Area

Cardiovascular Research, Cardiovascular Research; Cell Biology, Signal Transduction

Key Properties

• CAS Number: 62802-77-1
• MW: 293.28
• Purity: 99.84% (May vary between batches)
• Formula: C₁₆H₁₁N₃O₃
• SMILES: [O-][N+](=O)c1cccc(c1)C(=O)Nc1cccc2cccnc12
• Target: VEGFR
• Solubility: DMSO:5.24 mg/mL (17.87 mM)

Bioactivity

• Target IC50:
  VEGFR2:16.5 nM
• In Vitro:
  VEGFR-2-IN-29 Inhibited VEGF-induced proliferation in HUVEC cell.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

HUVEC, inhibit, Inhibitor, quinoline amide, WAY302159, WAY 302159, VEGFR2, VEGFR, Vascular endothelial growth factor receptor, VEGFR-2-IN-29

Compound Identifiers

PubChem CID

657169