VCP/p97 inhibitor-1

SKU: orb1690726

Description

VCP/p97 inhibitor-1 is a potent small molecule targeting the AAA+ ATPase VCP/p97 with an IC₅₀ of 54.7 nM. It disrupts protein homeostasis by inhibiting the degradation of ubiquitinated misfolded proteins via the proteasome. This compound is a valuable research tool for studying UPS-related pathologies, including cancer and neurodegenerative diseases, in cellular and animal models.

Research Area

Pharmacology & Drug Discovery; Cell Biology, Protein Biochemistry

Key Properties

• CAS Number: 2630950-38-6
• MW: 491.37
• Formula: C₂₄H₂₆BN₅O₄S
• SMILES: Cc1cc2c(NS(C)(=O)=O)cccc2n1-c1nc2CCCc2c(NCc2cccc(c2)B(O)O)n1
• Target: p97,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163321088