Vat-Cit-PAB-Monomethyl Dolastatin 10

SKU: orb1987592

Description

Vat-Cit-PAB-Monomethyl Dolastatin 10 is an antibody-drug conjugate (ADC) linker-payload featuring the potent tubulin inhibitor Monomethyl Auristatin E (MMAE). This construct is widely used in ADC research and development for evaluating targeted cytotoxicity in both in vitro and in vivo cancer models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1415329-13-3
• MW: 1176.53
• Formula: C₆₀H₉₃N₁₁O₁₁S
• SMILES: [H][C@]([C@@H](C)CC)([C@@H](CC(=O)N1CCC[C@@]1([H])[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)c1nccs1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](N)C(C)C)cc1)C(C)C |@:82|
• Target: Drug-Linker Conjugates for ADC,PROTAC Linker

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

89284617