VARS1-IN-1

SKU: orb3174824

Description

VARS1-IN-1 is a valyl-tRNA synthetase (VARS1) inhibitor with a Kd value of 0.213 μM. It suppresses the aminoacylation activity of VARS1, decreases the charging level of valine tRNA, and reduces the overall protein synthesis rate. Additionally, VARS1-IN-1 inhibits the growth and cell proliferation of aggressive tumors in PC3 prostate cancer xenograft models, making it a valuable tool in prostate cancer research.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 428830-84-6
• MW: 385.45
• Formula: C₂₁H₁₅N₅OS
• SMILES: O=C1N=C2SC(=NN2C(=N)C1=CC3=CNC=4C=CC=CC34)C=5C=CC(=CC5)C
• Target: DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

DNA/RNA Synthesis