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Catalog Number | orb1690005 |
---|---|
Category | Small Molecules |
Description | Varenicline |
Purity | 99.76% |
MW | 211.26 |
Biological Activity | Varenicline (CP 526555), a cytisine-based nicotinic ligand, is a potent partial agonist for the α4β2 nicotinic acetylcholine receptor (nAChR) with an EC50 value of 2.3 μM and acts as a full agonist for α7 and α3β4 nAChRs, with respective EC50 values of 18 μM and 55 μM [1]. Notably, its effectiveness and potential in smoking cessation treatments are underscored by its pharmacological profile [2]. |
CAS Number | [249296-44-4] |
Formula | C13H13N3 |
SMILES | N1=CC=NC2=CC3=C(C=C12)C4CNCC3C4 |
Storage | -20°C |
Note | For research use only |
> 98%(HPLC) | |
375815-87-5 | |
361.4 | |
C13H13N3·C4H6O6 |
> 98% (HPLC) | |
866823-63-4 | |
284.2 | |
C13H15Cl2N3 |
98.00% | |
[230615-23-3] | |
247.72 | |
C13H14ClN3 |
99.21% | |
866823-63-4 | |
284.18 | |
C13H15Cl2N3 |
99.90% | |
[375815-87-5] | |
361.35 | |
C13H13N3·C4H6O6 |