Valsartan Methyl Ester

SKU: orb1685563

Description

Valsartan Methyl Ester is a potent and selective angiotensin II type 1 (AT1) receptor blocker with an IC50 of 0.06 µM. This research compound is widely used in in vitro pharmacological studies and in vivo models of hypertension and cardiovascular disease to investigate the renin-angiotensin system.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 137863-17-3
• MW: 449.55
• Purity: 98.94% (May vary between batches)
• Formula: C₂₅H₃₁N₅O₃
• SMILES: CCCCC(=O)N(Cc1ccc(cc1)-c1ccccc1-c1nn[nH]n1)[C@@H](C(C)C)C(=O)OC
• Target: RAAS
• Solubility: DMSO:22.5 mg/mL (50.05 mM)

Bioactivity

• Target IC50:
  Ang II receptor:0.06μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

angiotensin II receptor

Compound Identifiers

PubChem CID

11561462