Valproic acid magnesium

SKU: orb3174687

Description

Valproic acid magnesium (Magnesium valproate) is an orally active HDAC inhibitor with an IC50 ranging from 0.5 to 2 mM. It suppresses the activity of HDAC1 (IC50, 400 μM) and induces the degradation of HDAC2. Additionally, it activates Notch1 signaling and inhibits the proliferation of small cell lung cancer (SCLC) cells. Valproic acid magnesium is applicable in research on epilepsy, bipolar disorder, metabolic diseases, HIV infection, and migraines.

Images & Validation

−

Key Properties

−

CAS Number	62959-43-7
MW	155.36
Formula	C₈H₁₅O₂.1/2Mg
SMILES	O=C(C(CCC)CCC)[O-].O=C(C(CCC)CCC)[O-].[Mg+2]
Target	Autophagy,HDAC,HIV Protease,Mitophagy,Gamma-secretase,Apoptosis,Endogenous Metabolite

Storage & Handling

−

Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Quick Database Links

Gene Symbol

Autophagy,HDAC,HIV Protease,Mitophagy,Gamma-secretase,Apoptosis,Endogenous Metabolite

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols