Valproic acid magnesium

SKU: orb3174687

Description

Valproic acid magnesium (Magnesium valproate) is an orally active HDAC inhibitor with an IC50 ranging from 0.5 to 2 mM. It suppresses the activity of HDAC1 (IC50, 400 μM) and induces the degradation of HDAC2. Additionally, it activates Notch1 signaling and inhibits the proliferation of small cell lung cancer (SCLC) cells. Valproic acid magnesium is applicable in research on epilepsy, bipolar disorder, metabolic diseases, HIV infection, and migraines.

Research Area

Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 62959-43-7
• MW: 155.36
• Formula: C₈H₁₅O₂.1/2Mg
• SMILES: O=C(C(CCC)CCC)[O-].O=C(C(CCC)CCC)[O-].[Mg+2]
• Target: HDAC,Gamma-secretase,Mitophagy,HIV Protease,Apoptosis,Endogenous Metabolite,Autophagy

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

HDAC,Gamma-secretase,Mitophagy,HIV Protease,Apoptosis,Endogenous Metabolite,Autophagy