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Val-Ala-PABC-N(Mesylpropane)-Exatecan

SKU: orb2802414

Description

This product is a cleavable ADC linker-drug conjugate, combining a Val-Ala-PABC-N(Mesylpropane) linker with the payload Exatecan, a potent topoisomerase I inhibitor. It is designed for research into antibody-drug conjugates (ADCs) for targeted cancer therapy in both in vitro and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2842021-73-0
MW948.02
FormulaC46H54FN7O12S
SMILESN(C(COCN(C(OCC1=CC=C(NC([C@@H](NC([C@H](C(C)C)N)=O)C)=O)C=C1)=O)CCS(C)(=O)=O)=O)[C@@H]2C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=C(CC2)C(C)=C(F)C7
TargetMicrotubule Associated,Drug-Linker Conjugates for ADC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information