αvβ5 integrin-IN-2

SKU: orb2565000

Description

αvβ5 integrin-IN-2 (Cpd_AV2) is a small molecule inhibitor that binds the β-propeller pocket of ITGAV, destabilizing the αVβ5 integrin heterodimer to induce apoptosis. This mechanism supports its research use in studying integrin biology, cancer cell survival, and potential therapeutic strategies in both cellular and animal models.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1005104-60-8
• MW: 480.69
• Formula: C₃₂H₄₀N₄
• SMILES: CC1CC(C2=CC3=C(C=C2)C=CC=C3)NCCNC(CC(C)NCCN1)C4=CC5=C(C=C4)C=CC=C5
• Target: Apoptosis,Integrin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

430095