V-9302 hydrochloride

SKU: orb3137081

Description

V-9302 hydrochloride is a competitive transmembrane glutamine flux antagonist that selectively targets the amino acid transporter ASCT2/SLC1A5. V-9302 hydrochloride impedes glutamine uptake mediated by ASCT2 (IC50=9.6 μM), inhibits the mTOR signalling pathway, increases oxidative stress and ROS levels, induces autophagy, and exerts antitumour effects.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2416138-42-4
• MW: 575.14
• Purity: 97.31% (May vary between batches)
• Formula: C₃₄H₃₉ClN₂O₄
• SMILES: C(N(CC1=C(OCC2=CC(C)=CC=C2)C=CC=C1)CC[C@@H](C(O)=O)N)C3=C(OCC4=CC(C)=CC=C4)C=CC=C3.Cl
• Target: mTOR,ROS,ASCT,Autophagy

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

mTOR,ROS,ASCT,Autophagy