V-11-0711 HCl

SKU: orb2567336

Description

V-11-0711 HCl is a potent and selective small molecule inhibitor of choline kinase alpha (ChoKα). It is utilized in cancer metabolism research to investigate oncogenic signaling and has demonstrated antitumor activity in both cellular and animal models of various cancers.

Research Area

Neuroscience

Key Properties

• MW: 458.03
• Purity: >99.99% (May vary between batches)
• Formula: C₂₇H₃₆ClNO₃
• SMILES: O[C@@]([C@]1([H])C2CCN(CC2)C1)(C3=CC=CC=C3)CCC4=C(C=CC=C4)OC5CCOCC5.Cl
• Target: AChR

Bioactivity

• Target IC50:
  ChoKβ:220 nM|ChoKα:20 nM
• In Vitro:
  V-11-0711 inhibited recombinant human ChoKα with an IC50 of 20 nM, and showed 11 fold less activity against ChoKβ (IC50 220 nM).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

choline kinase alpha (ChoKα), V-11-0711 HCl(1428339-47-2 Free base), V110711HCl(1428339472Freebase)

Compound Identifiers

PubChem CID

172652687