Uvaol

SKU: orb1297178

Description

Uvaol, a pentacyclic triterpene found in olives and virgin olive oil, exhibits anti-inflammatory, anti-proliferative, and vasorelaxant properties. It is utilized in research areas such as cardiovascular biology and oncology, with studies demonstrating its bioactivity in both cellular and animal models.

Research Area

Cell Biology, Metabolism Research, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 545-46-0
• MW: 442.72
• Purity: 99.77% (May vary between batches)
• Formula: C₃₀H₅₀O₂
• SMILES: C[C@@H]1CC[C@]2(CO)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C
• Target: PPAR,JNK,Endogenous Metabolite,Apoptosis
• Solubility: Ethanol:8 mg/mL (18.07 mM);DMSO:1.5 mg/mL (3.39 mM);10% EtOH+90% Corn Oil:0.5 mg/mL (1.13 mM)

Bioactivity

• In Vitro:
  Uvaol decreased collagen I and galectin 3 levels induced by angiotensin II in cardiac myofribroblasts. Uvaol attenuates pleuritis and eosinophilic inflammation in ovalbumin-induced allergy in mice.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PPAR, Uvaol, Endogenous Metabolite, EndogenousMetabolite, allergy, antioxidant, oil, Pleuritis, JNK, inhibit, inflammation, Inhibitor, eosinophilic, Human Endogenous Metabolite

Compound Identifiers

PubChem CID

92802