UU-T03

SKU: orb746468

Description

UU-T03 is the ethyl ester derivative of UU-T02, which is a potent, selective inhibitor of β-catenin/Tcf4 interaction with Ki of 1.36 uM; exhibits growth inhibition of SW480 cells with IC50 of 10.77 uM; downregulates the transcription of AXIN2, LGR5, cyclin D1, and c-Myc in dose-dependent manners in SW480 cells.

Key Properties

• CAS Number: 1586007-00-2
• MW: 721.204
• Purity: >98%
• Formula: C₃₇H₄₁ClN₄O₉
• SMILES: C(C)(O)(=O)[C@H](CCC(CC)(O)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CC1=CC2=C(C=CC(Cl)=C2)N1)CC1=CC=C2C(C=CC=C2)=C1)CC(OCC)=O

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only