USP7-IN-9

SKU: orb1744319

Description

USP7-IN-9 is a potent and selective USP7 inhibitor (IC50 = 40.8 nM). It triggers apoptosis and G0/G1/S phase arrest in leukemia cells like RS4;11, modulates key cancer-related proteins (e.g., downregulating MDM2, upregulating p53), and is a valuable chemical probe for oncology research in cellular studies.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry

Key Properties

• MW: 779.08
• Formula: C₃₂H₃₃ClF₆N₆O₈
• SMILES: COC(C1=CC=C(C[NH+]2CCC(CC2)(O)CN(C=NC3=C4C5=CC=C(C[NH3+])C=C5)C(C3=NN4C)=O)C(Cl)=C1)=O.O=C([O-])C(F)(F)F.O=C([O-])C(F)(F)F
• Target: Apoptosis,Others,DUB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163322405