USP7-IN-16

SKU: orb2814085

Description

USP7-IN-16 (Compound 61) is a potent and selective USP7 inhibitor, demonstrating single-digit nanomolar IC50 values in biochemical (FLINT) and cellular (MM.1S) assays. This compound has shown in vivo antitumor efficacy in mouse models, supporting its utility as a chemical probe for oncology research, particularly in studying ubiquitin-specific protease pathways.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 2166587-77-3
• MW: 787.93
• Formula: C₄₃H₄₅N₇O₆S
• SMILES: O=C1C2=C(N(C=C2)C3=CC(OC)=CC(OC)=C3)N=CN1CC4(O)CCN(C(=O)[C@H]5[C@@H](CN(C(=O)C=6SC(=NC6C)C=7C=CC(C)=NC7)CC5)C8=CC=CC=C8)CC4
• Target: Others,DUB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138540402