USP7-IN-12

SKU: orb2278154

Description

USP7-IN-12 (compound 1) is a potent and orally bioavailable deubiquitinase inhibitor with an IC50 of 3.67 nM against USP7. It demonstrates robust antiproliferative effects in cellular assays and has shown promising in vivo activity in preclinical cancer research models, supporting its use as a chemical probe for oncology and ubiquitin-proteasome system studies.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 2763698-01-5
• MW: 551.07
• Formula: C₂₉H₂₈ClFN₄O₂S
• SMILES: C(N1C2=C(C=C(Cl)C=C2C=C1)C3=C4C(C=C(CN5C(=O)C6C(C5=O)C6(C)C)S4)=NC=C3)C7(F)CCNCC7
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162744931