USP5-IN-1

SKU: orb1689813

Description

USP5-IN-1 (compound 64) is a selective small molecule inhibitor targeting the ZnF-UBD domain of deubiquitinase USP5 with a KD of 2.8 µM. It blocks USP5's catalytic activity against di-ubiquitin substrates and serves as a valuable chemical probe for in vitro studies investigating ubiquitin signaling and cancer-related pathways.

Research Area

Cell Biology, Molecular Biology, Protein Biochemistry

Key Properties

• MW: 437.9
• Purity: 99.53% (May vary between batches)
• Formula: C₁₉H₂₀ClN₃O₅S
• SMILES: O=C(O)CNC(=O)C1=CC=C(S(=O)(=O)N2CCC(C3=CC=C(Cl)C=C3)CC2)C=N1
• Target: DUB
• Solubility: DMSO:48.33 mg/mL (110.37 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

USP5, USP5IN1, USP5-IN-1

Compound Identifiers

PubChem CID

155921308