USP1-IN-6

SKU: orb2277675

Description

USP1-IN-6 (Compound 11) is a potent, sub-50 nM inhibitor of the USP1 deubiquitinase. It exhibits comparable cellular activity, inhibiting the growth of MDA-MB-436 breast cancer cells. This tool compound is used in vitro to study DNA damage response pathways and oncology research, particularly in BRCA-deficient contexts.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 2925547-95-9
• MW: 560.57
• Formula: C₂₉H₂₇F₃N₈O
• SMILES: C(C)(C)N1C(C23C4C5C2C6C3C4C56CN7C=8C(C=N7)=CN=C(N8)C=9C(=NC=NC9OC)C%10CC%10)=NC(C(F)(F)F)=C1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168510618